What is melanoma?

A melanoma is a malignant formation that develops from skin pigment cells - melanocytes. Melanocytes are mainly located in the skin and pigmented epithelium of the retina. Accumulations of melanocytes mould moles (birthmarks).

Melanocytes release the pigment melanin and protect the body from the influence of ultraviolet radiation. That is how a tan appears.

The mechanism of melanoma occurrence is not thoroughly studied. Like other cancers, melanoma occurs due to spontaneous changes in the genetic code, exposure to harmful substances and adverse factors. Moles traumas lead to the development of melanoma as well.

The division of pigment cells and the cell growth run out of control. In contrast to benign formations, melanoma can invade other tissues and organs. Melanoma along with the current of lymph or blood can migrate through the body, affecting all its systems (metastasize).

A melanoma is a malignant tumor of the skin that occurs from the uncontrolled growth of melanocytes and is characterized by extremely rapid development.

Every hour one person in the world dies from melanoma. It is expected that the number of patients with such a diagnosis in the coming years will increase, which means that each of us should pay particular attention to the moles.

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Types of skin cancer

Along with melanoma, there are other malignant lesions including basal cell carcinoma (basalioma) and squamous cell carcinoma (88% of all cancerous skin lesions).

It should be reminded that skin cancer and melanoma are not the same. Cancer is formed from epithelial cells (skin), while melanoma - from pigment cells (melanocytes).

Types of skin cancer

Basalioma

Squamous cell carcinoma

Melanoma

Features

  • develops from the basal skin layer
  • leads to local tissue destruction
  • does not metastasize
  • develops from the cells of the epidermis
  • develops rapidly
  • metastasizes
    • develops from melanocytes pigment cells
    • grows rapidly
    • actively metastasizes
    • is a malignant type of skin cancer

Frequency

is very common

isn't very common

is a rare, but the most dangerous among all skin cancer types

Looks like

a node similar to a furunculus, which does not point for a long time; can be ulcerateв in time, destroying the skin area

a spheroma can go deep inside or rise above the skin; be ulcerated and painful

a nonsymmetrical mole with an uneven contour, larger than usual; is painful, itchy, swell, bleed

Photo

basalioma photo

squamous cell carcinoma

melanoma photo

What is the difference between melanomas and moles?

In 60% of cases, melanoma develops from already existing on the body of moles, nevi and pigment spots.

Moles are the pigmented cells everyone has. In fact, we are not born with them: they appear in early childhood and can disappear at a more mature age. Often, new moles are formed on the body to 40 years. Normal moles do not change during life; they are clear and homogeneous. Melanoma shows the dynamics: if the mole is malignant, it grows and changes.

How does melanoma develop?

Cancer cells begin to intensively divide and rapidly grow, spreading in the epidermis layer, and then growing into a deep layer of skin - the dermis, where the blood and lymph vessels are located. Once the melanoma grows deep into the dermis, its cells can enter the lymphatic vessels and spread to other organs through them. The process of spreading melanoma cells through lymphatic vessels is called metastasis, and distant tumors that are formed from melanoma cells are metastases. First melanoma gives metastases to the near lymph nodes, and then to distant organs - the lungs, the brain, the liver, and bones.

How quickly does a melanoma grow?

A melanoma develops rapidly: it can take 6-8 months since first signs of a tumor to the development of metastases.

Symptoms of dangerous moles

1. The asymmetric form

A normal mole that does not threaten your life should be symmetrical, i.e., round or oval, its parts should be equal to each other. The boundaries of a mole are clear, even and bright. A dangerous mole сan have any shape with torn, fuzzy, blurred edges. If there is such a birthmark on your body - visit a specialist immediately!

2. Color

A harmless mole is a smoothly brown or dark brown, it is evenly colored, has no stains or other colors. Potentially, the cancerous mole is uneven сolor, has spots and impurities of different colors. Check the coloration of the moles on your body, ask your relatives to examine the moles that are in places inaccessible to your eyes.

3. Size

All moles exceeding 6mm should be examined by a doctor! Moles bigger than pencil eraser can be malignant.

4. Transformation of moles

Pay attention to changes in your moles. A sudden change of color and shape, and/or its increase is the evidence of potential danger.

5. Unprotected skin

Often visits the beach or solarium without using sunscreen risk your health. It is proved that ultraviolet rays increase the probability of a healthy mole degenerating into a malignant tumor by 74%.

How to distinguish a mole from a melanoma

At the initial stages of melanoma, it is not easy to distinguish it from an ordinary mole. Therefore, one must remember that any mole which isn't similar to others in the body are subject to control.

The table contains a list of indicative signs of melanoma. It will help to detect the safety of your moles.

Criterion

Benign nevus (mole)

Melanoma (malignant mole)

Formation of the skin

symmetric

asymmetric

Boundary

even and precise contour

uneven, imprecise contour with a jagged or blurry contour

Color

homogeneous, most often brown

nonhomogeneous, black or red color, interspersed with a different color

Size

not larger than a pencil eraser

larger than 6mm in diameter

Changes

isn't vulnerable to changes; can disappear with years

grows and changes

Symptoms

no unfavorable symptoms

peeling, itching, puffiness, redness, ulcers, bleeding

How does a malignant mole look like?

Typically, a melanoma looks like a flat spot on the skin, a bosselation or knot rising above its surface. The color of the formations can be saturated black or dark brown. Due to this feature, melanoma is called "black skin cancer."

Sometimes malignant moles do not differ from the skin or have a white, red color.

How does melanoma look like?

At an early stage, melanoma is hard to differentiate from an ordinary mole. It appears as a stain or nodule on the skin, mucous membrane or iris of the eye. If you notice a mole in the size of more than 2mm, and it causes inconvenience (growing, changing color, hurting or itching), you should see a doctor to determine the malignancy of the formation. At a later stage, nearby tissues are affected by cancer, and the lymph nodes become inflamed.

Lymph nodes are a kind of filter protecting the body from harmful factors, including microbes, viruses, toxic substances and malignant cells. It makes lymph nodes increased and painful in inflammatory processes and various diseases.

General health with metastatic melanoma is getting worse. A patient notices weight loss and weakness, which signalize the all body systems disorder. Everyone should remember the earlier the diagnosis of melanoma is established, the higher the curability of the disease.

How to suspect melanoma from the symptoms?

  • Have you or your relatives been diagnosed with melanoma or other cancers?
  • Are there any new moles since your last examination?
  • Does the mole have an uneven boundary?
  • Is a mole asymmetric?
  • Had an old mole (nevus) increased since the last exam?
  • Does the mole itch, flake or bleed?
  • Has a mole changed color or its color become inhomogenous?

If you have at least one positive answer, you should consult with a dermatologist or oncodermatologist!

Causes of melanoma

A melanoma is considered one of the most dangerous types of cancer in the world, the number of patients with this diagnosis is growing rapidly. Today, it has not yet been possible to definitively determine the specific cause of melanoma development, but factors that significantly increase the risk of its development are known. A person who knows the factors, can limit them, and reduce the risk of developing melanoma.

Risk Factors in the melanoma development:

  • genetic predisposition

If someone in your family has been diagnosed with melanoma, you are in a group with higher risk. In this case, it is necessary to regularly inspect the skin and with the slightest suspicion of melanoma consult with a doctor.

  • ultraviolet radiation (sun, solar lamps, solarium)

Lying in the sun, love of a solarium or solar lamps are a sure way to excessive insolation of the body, as well as burns, which are especially dangerous in childhood. They can lead to the development of melanoma in adulthood.

  • multiple and/or atypical moles

The more moles are on the body, the more likely they can transform into malignant formations. Timely control will reveal suspicious elements on the skin and carry out treatment on time.

  • fair skin phototype

The skin of people with fair or red hair is poorly protected from ultraviolet light. Such people are prone to sunburn, and statistically, they have melanoma more often.

  • decreased immunity

The immune system protects us not only from viruses and bacteria but also from the formation of malignant cells in the body. The activity of immunity may decrease due to chronic infections, and taking of certain medications.

  • pigment xeroderma

This is a fairly rare hereditary disease, in which the skin is not able to recover after exposure to sunlight. The skin of people with such a diagnosis burns, which increases the risk of developing melanoma and other skin cancers.

How to prevent melanoma

A healthy lifestyle, timely treatment of infections and viral diseases is an important step in the prevention of cancer. Certainly, they cannot completely protect a person against the risk of melanoma and other cancers, however, reduces the chance of getting sick, facilitates the body functioning and treatment as well.

If you miss possible signs of the disease, a melanoma will be manifested in uncomfortable symptoms, such as itching, flaking, bleeding, swelling, and redness.

To determine melanoma, it is essential to notice any changes in the skin. The body inspection should be made in front of the mirror in full height. Use a hand mirror to inspect the back areas. You may also ask your closed one to examine hard-to-reach areas of the skin.

With the help of a special to-do-list, you will be able to notice suspicious formations on the skin at home promptly.

How to inspect moles at home

  1. Choose the most suitable time for the regular self-examination.
  2. Keep a diary and take notes on the date of the examination, moles that have recently appeared and cause a desire to observe.
  3. Take photos of the moles for a visual fixation of the changes.
  4. Find a place for examination - it should be a bright room with a large mirror. To inspect hard-to-reach places, use a small hand mirror. A close person can also help you with the examination.
  5. Inspect the entire surface of the skin, including face, ears, neck, armpits, chest, sides, palms, fingers, front and back surfaces of the legs, genitals.
  6. Pay attention to the nails and interdigital areas; visually examine the reflections of your eyes and skin in places that come in contact with clothing and shoes (for example, with underwear, glasses, belt). Women should also examine the skin under the breast.
  7. Examine the skin of the head - use a comb, hair dryer and mirror to lift the hair strands and check for moles.
  8. Measure the size of your moles with a ruler and write down their size.
  9. Moles that differ from others in color, shape, texture, touch them gently to determine if they cause unpleasant sensations, and to understand how much they rise above the skin.
  10. If you find suspicious moles or indurations on the skin, fix their size, position on the body and visit a doctor for a consultation.

Melanoma is a very dangerous disease. This type of skin cancer does not arouse suspicion until it passes to the later stages. However, timely diagnostics and simple rules of protection will help to protect yourself.

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