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Dr. Corrado Lodigiani has been assistant at the Thrombosis Centre of Humanitas research Hospital from 1998 to 2013 and he became Unit Director in 2013. 

Humanitas Thrombosis Center is a state-of-the-art service for the proper management of the diagnosis and therapy of venous thromboembolic pathology (deep and superficial venous thrombosis, pulmonary thromboembolism, visceral venous thrombosis) and arterial (myocardial infarction, cerebral stroke, peripheral arterial disease). 
Other also rare diseases treated are atypical thrombosis, such as the vascular circulation of the retina, the hearing system and the placental circulation during pregnancy. 

Dr. Lodigiani adopts the multidisciplinary approach and works in collaboration with all medical and surgical specialties. In particular, he carries out clinical and instrumental diagnostics (vascular ecocolordoppler) and research on the causes, diagnosis and therapy of thrombotic and bleeding disorders, congenital and acquired. His clinical activity also involves the diagnosis and management of patients suffering from bleeding diseases, such as haemophilia, von Willebrand’s disease and platelet diseases.

Medical areas of interest:  

In recent years, he has devoted himself with particular interest to the testing, in the role of Principal Investigator in International Clinical Studies, of new antithrombotic drugs and, above all, anticoagulants, which are about to be marketed and will constitute a valid and safe alternative to traditional oral anticoagulant therapy (DOACs). He is also working, with great interest, on researching the causes of idiopathic infertility and the usefulness and effectiveness of some therapeutic strategies, such as the use of anticoagulant drugs, improving the results of artificial insemination procedures. He is the author of numerous articles in international scientific journals and speaker at numerous national and international conferences.

Dr. Daniela Pini is the Head of the Cardio-respiratory rehabilitation Unit.

Medical areas of interest: Dr. Daniela Pini has been working and researching heart failure and has gained considerable experience in the management of advanced forms of this pathology. She is also very interested in the evaluation and "overall" management of patients suffering from this disease, which mainly affects elderly people and who already have other chronic diseases, which, if neglected, can easily impair the effectiveness of treatment for heart failure itself.

Research areas of interest: new therapies for advanced heart failure: replacement therapy of the heart with mechanical assistance devices to the circulation or heart transplant. New drugs and devices. Multidisciplinary patient management programs.

Further information of interest: thanks to the high competence of cardiosurgeons, electrophysiologists and hemodynamists, Humanitas can count, as a clinical cardiologist, on a team that allows it to offer the patient all the range of therapeutic options for heart failure.

From June 2000 to October 2001 she was Visiting Assistant Professor at the Cardiovascular Division Hospital of the University of Pennsylvania. During this period, she worked in the Heart Failure/Heart Transplantation Program, where she participated in the management of patients with advanced heart failure waiting for transplantation, dealing in particular with medical complications in patients with mechanical assistance devices. She has also worked with kidney, kidney-pancreas, pancreas-insulae, lung, liver and heart transplant teams, dealing with the multiple aspects of managing solid organ transplant recipients.

She worked in the Niguarda Ca' Granda Hospital, at the Cardiomyopathy and Heart Transplantation Service, dealing mainly with patients with advanced heart failure and undergoing a cardiac transplant.

Dr. Pini is a member of the coordination committee of the Decompensation Area of the National Association of Medical Hospital Cardiologists – ANMCO. In the last two years she has been mainly concerned on building a network of “heart failure clinics” on the national territory.

Dr. Federico Pessina is the Cranial Neurosurgey Unit Director.

Medical areas of interest: Brain tumors, glioblastomas, low grade gliomas, brain metastases, meningiomas, neuromas, cavernous angiomas, brain aneurysms

Surgical treatment with brain mapping techniques, awake and minimally invasive surgery of all central nervous system tumors.

Surgical treatment of highly complex tumors of the skull base and cranio-cervical hinge: meningiomas, neuromas, craniopharyngiomas, brain stem tumors.

All the tumor pathologies described above are addressed after multidisciplinary multi-specialist evaluation.

The surgical approach is customized to the patient and to the type of lesion, making use of the most advanced intraoperative techniques for malignant brain tumors (neuronavigation, intraoperative neurophysiology, intraoperative CT) and more complex approaches (anterior, posterior and combined petroosectomies, minimally invasive accesses) for benign diseases of the skull base such as meningiomas and neuromas.

Research areas of interest: Experimental protocols in the treatment of glioblastomas

- Prospective protocols in the treatment of brain metastases

- Role of surgical removal and integrated treatments in glioblastomas and malignant brain tumors

- Intracranial meningiomas

- Cadaver lab dissection

Author of more than 60 scientific publications and 5 book chapters, he is member of Italian Society of Neurosurgery (SINCH).

In 2018 he joined the Scientific Committee of European Society of Neuroncology (EANO) and the Skull Base Surgery Committee of World Federation of Neurosurgical Society (WFNS).

Specialized training: 

Prof. Pessina obtained his Degree in Medicine and Surgery in University of  Insubria,  Varese, where he also completed his Residency Program.

From 2007 to 2008 he covered the role of Clinical Fellow in Neurosurgery in Lausanne University Hospital, focusing on image-guided intrinsic brain tumors resection and vascular neurosurgery

In 2018 he covered the Skull Base fellow position in Lariboisiere Hospital, Paris, fully dedicating to skull base surgery and hands-on dissection practice and teaching.

Since 2022, he is Full Professor in Neurosurgery (MED/27) in Humanitas University

Additional information of interest:

Member of the Scientific Committee of the European Association of Neuroncology (EANO)

Publications:  https://www.ncbi.nlm.nih.gov/pubmed/?term=Pessina+Federico

Professor Santoro is heavily involved in research, with interest in many topics, such as the development of new cancer drugs and new biological therapies, interests for solid and haematological tumours, and not only he treats cancer survivors but also patients with comorbidities.

He has worked in Humanitas Research Hospital for 22 years. Professor Santoro’s post-graduate research was carried out at the Unité de Development Therapeutique (Institut de Cancerologie et d’Immunogenetique, Villejuif of Paris) from 1974 to 1975, and in the Division of Medical Oncology of the National Cancer Institute of Milan from 1976 to 1977. 

In 1977, he specialized in Clinical and Laboratory Haematology at University of Rome. In 1979, he completed his fellowship post-graduate work in the Memorial Sloan Kettering Cancer Center of New York and later, at Stanford University. In 1980, he specialized in oncology at the University of Genoa. 

Current Teaching Activity: Professor Santoro worked as Contract Professor at the Specialization School in Clinical Pathology ad Pavia University from 1992 to 1997. Also, from 1993 to 2002 he has been President of the Rare Tumour Group. Now he is full professor at Humanitas University. 

Current Positions: 

• .Since 1997, he is the Director of the Department of Medical Oncology and Haematology, at Istituto Clinico Humanitas, Milan. Also, he is Member of the Ethics Committee of Istituto Clinico Humanitas and Director of Clinical Research in the same Institute since 2007.
• - Since 2008, he is Member of the Planning Committee, Ministry of Work and of Health and Social Politics, Rome, Italy.
• - Since October 2008, Professor Santoro is Counsellor of the Board of Directors of the Fondazione Humanitas for Research of Rozzano, Italy.
• - Since November 2008, he is Expert Member of the National Centre for the Prevention and Control of Disease, Ministry of Work and of Health and Social Politics (Rome, Italy).
• - Since February 2009, he is National Representative preparatory actions for the "European Partnership for Action against Cancer" Ministry of Work and of Health and Social Politics (Rome, Italy).
• - Since February 2009, Professor Santoro is member of National Italian Committee on the Research Network in Oncology, Ministry of Work and of Health and Social Politics (Rome, Italy).
• - Since May 2009, he is Coordinator of the Oesophageal-Stomach Cancer Group Coordinator of the Liver and Biliary Tree Cancer Group, Regional Oncology Commission – Lombardy Oncology Network.

In addition, Professor Santoro’s unique expertise was recognized through numerous awards, such as the Managing Doctor of the Year award (2013), the City of Siena S. Caterina d’Oro Award (2013, Serra Association Award for scientific research) and social and healthcare commitment (Salerno, 2009). 

Publications: santoro%a - Search Results - PubMed (nih.gov) 

Professor Antonino Spinelli is the Director of the Division of Colon and Rectal Surgery at Humanitas Research Hospital.

The Division of Colon and Rectal Surgery is one of the most important centres for colorectal disease, especially for procedures of sphincter preservation for rectal tumours, but also for chronic inflammatory bowel disease (Crohn disease, ulcerative rectal colitis…) and the surgical treatment of diverticular pathologies. 

Professor Spinelli carries out a constant research on minimally invasive surgeries, including the single-port surgery, mini-laparoscopy, low-impact surgery and trans-anal techniques (TATME, TAMIS, TTSS). Furthermore, the advanced postoperative recovering is another area of his interest.

He graduated as MD in 2001 at University of Milano. During his education, he won several scholarships: he trained ad University of Berlin Charitè for two years at the Department of General, Visceral and Transplantation Surgery. Also, he obtained his PhD on Surgical Phsyiopathology with a dissertation on enhanced recovery for laparoscopic colorectal surgery in 2011. 

Current Teaching Activity: he is Full Professor of Surgery at Humanitas University. 

Also, Professor Spinelli is general Secretary of the European Society of Coloproctology (ESCP) and Board Member of the Guidelines Committee (GulCom) of the European Crohn Disease and Colitis Organization (ECCO). He is Fellow of the American Society of Colon and Rectal Surgery (FASCRS), Honorary Fellow of the Czech Society of Surgery (CSS) and Honorary Member of the Brazilian College of Digestive Surgery (CBCD). 

He is a member of the International Organization for the study of Inflammatory Bowel Disease (IOIBD) and several other national and international scientific societies. 

In addition, Professor Spinelli serves as Associate Editor for Colorectal Disease (Journal of the Association of Coloproctology of Great Britain & Ireland, Royal College of Surgeons of England, of the European Society of Coloproctology and of the Spanish Society of Coloproctology – Asociación Española de Coloproctología), Diseases of the Colon and Rectum (official journal of the American Society of Colon and Rectal Surgeons), Journal of the Anus, Rectum and Colon (official journal of the Japan Society of Coloproctology).

He is Editorial Board Member of the Journal of Crohn’s Colitis (official journal of the European Crohn’s Colitis Organization), Advisory Board of Coloproctology (official journal of the German Society for Coloproctology – Deutsche Gesellschaft für Koloproktologie) and Editorial Board Member of Updates in Surgery (official journal of the Italian Society of Surgery – Società Italiana di Chirurgia).

Prof. Andrea Lania has graduated at the Università degli Studi of Milan and is specialized in endocrinology. He is the Unit Director of Endocrinology and Diabetology in Humanitas Research Hospital and his specialization is pituitary diseases, pituitary adenomas, thyroid cancer, pancreatic neuroendocrine tumors, poorly differentiated neuroendocrine carcinomas.

Medical areas of interest:
Pituitary tumors, hypopituitarism, acromegaly, Cushing’s disease and syndrome, neuroendocrine tumors, thyroid and thyroid diseases, adrenal and adrenal diseases, hypogonadism.

Research areas of interest:
Study of the pathogenetic mechanisms of pituitary and neuroendocrine tumors, of the molecular mechanisms responsible for the different response of pituitary and neuroendocrine tumors to medical therapy.

Prof. Lania published 198 peer-reviewed papers (Google Scholar H-Index 47; Scopus H-Index 38, cit tot 4604)

Prof. Lania has a long standing expertise in the field of intra-cellular signaling in endocrine tumors. In particular, in the past ten years, he contributed to analyze the role of PKA regulatory subunits in the pathogenesis and control of cell proliferation of endocrine tumors. Moreover, he contributed to define the role of SSTR5 domains involved in the intracellular trafficking of this receptor in human pituitary cells and to analyze the impact of DR2R and SSTR2&5 polymorphic variants on both the clinical outcome and response to medical treatment in patients with pituitary tumors.

Recently, he contributed to identify the role of cytoskeleton protein FLNA in mediating both intracellular signaling and membrane targeting of somatostatin type 2 receptor and D2R in pituitary and pancreatic neuroendocrine tumors. Finally, he contributed to explore the intracellular mechanisms possibly involved in mediating the interplay between drugs commonly used in the treatment of neuroendocrine tumors.

Previous experience:
2005-2008 Fondazione Ospedale Maggiore Policlinico IRCCS, Milan, Italy
Director of Endocrinologic Day Hospital and surgery on pituitary disorders. 

Publications: https://www.ncbi.nlm.nih.gov/pubmed?term=lania%20A 

Prof. Alessandro Repici is the Director of the Gastroenterology and Digestive endoscopy Unit in Humanitas Research Hospital. Graduated in Medicine and Surgery in 1990 and the following year he won a scholarship at the Department of Gastroenterology Molinette hospital in Turin, where he began his practice in digestive endoscopy. In 1992, he worked with Prof. Claude Liguory as a fellow at the American Hospital in Paris.

In 1994 he became a specialist in Gastroenterology and Digestive Endoscopy at the University of Messina and worked in the Department of Gastroenterology, Ospedale Maggiore Molinette of Turin.

In the following years, he has been working at the Service of Digestive Endoscopy of Altona Hospital in Hamburg, directed by prof. Hagenmuller, and in the Department of Gastroenterology Molinette Hospital in Turin, directed by prof. Rizzetto. In 1999, he was a Research Fellow at the Center for Oncological and Operative Endoscopy of Wellsley Hospital in Toronto.

He teaches Gastroenterology and Digestive Endoscopy at the School of Specialization in Oncology since 2000, at the University of Turin since 2004 and Endoscopy Diagnostic Techniques and Operations at the School of Specialization in General Surgery I and II of the University of Turin.

The clinical activity and research of Prof. Repici mainly focuses on the development of new endoscopic techniques in the field of diagnosis and therapy, with particular attention to new methods of endoscopic removal of cancerous lesions and early in the palliation of advanced gastrointestinal malignancies.

Prof. Repici is coordinator, principal investigator and co-investigator in more than 50 studies, including phase II and III for FDA and EMA approval of new molecules and new instruments for diagnostic and operational endoscopy. 

Prof. Repici collaborates on research projects in the field of endoscopy with the University of Rotterdam, in Haifa, in New York and with several Italian centers. He is a member of various national and international scientific society of Gastroenterology and Digestive Endoscopy.

Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=repici+alessandro

Prof. Leonardo Maradei is specialised in orthopaedics and traumatology and is the Director of the Foot Surgery and Minimally Invasive Operations Unit in Humanitas Research Hospital. 

Prof. Leonardo Maradei performs surgery on the foot with minimally invasive techniques and arthroscopic surgery. After his specialization he deepened his studies in arthroscopic surgery of the shoulder and the knee at the Mississippi Sports Medicine & Orthopaedic Center (USA), under the guidance of prof. F. H. Savoie. He has developed considerable experience in shoulder prosthetic surgery as a pupil of prof. Mario Randelli. 
His research is focused on the development of new prosthetic materials for the shoulder. During his years in Humanitas he has performed more than 2000 surgeries on the foot, more than 1000 on the knee and more than a 1000 on the shoulder. 

Dr. Maradei is a professor at Università Statale of Milan where he teaches Medicine and Surgery - Lessons on minimally invasive surgery of the shoulder and knee.

Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=maradei+leonardo

Prof. Alberto Albanese is the Neurology Unit Director at Humanitas Research Hospital. Until recently – Department Head of Neuroscience at the Institute of Neurology Carlo Besta (Milan). In 1977 prof. Albanese received his degree in medicine and surgery, in 1981 – in neurology, and in 1985 – in psychiatry. His professional experience began with the founding of the Department of “disorders of Parkinson’s and violations of the musculoskeletal system” at the clinic “A. Gemelli “in Rome in 1984, which he led until 1996. From 1996 to 2000 prof. Albanese was the Head of the Neurological University Clinic of Lausanne (Switzerland) and a professor of Neurology in the University.

From 2000 to 2015 he was Head of Neuroscience Department at the Institute of Neurology Carlo Besta (Milan).

Prof. Albanese is a professor of neurology at the Institute of Neurology at the Catholic University of the Sacred Heart (Milan), Director of the post-graduate course “Diagnosis and treatment of movement disorders and degenerative neurological diseases” at the Foundation Neurological Institute “C. Besta”, as well as an adjunct professor at the School of Specialization in Neuroscience at the University of Milan Bicocca.

Prof. Albanese is the president of “Italian Association of Parkinson’s disease and movement disorders” and “Italian Association for the Study of the autonomic nervous system” (which are part of “Italian Community of Neuroscience”). He is also an honorary member of the “French Community of Neuroscience.” The professor is a moderator and speaker at major national and international neurological conferences, he organized several symposia dedicated to Neurology, collaborates with numerous national and international research centers, which are studying Parkinson’s disease, movement disorders and degenerative neurological diseases. Prof. Albanese has been repeatedly receiving research fundings from the following government agencies: the Ministry of Health, Ministry of Science and Research, National Research Council, the British Council, the Swiss National Research Council.

He is one of the greatest Italian experts on the diagnosis and treatment of neurological diseases and movement disorders, Parkinson.

He has extensive experience in the use of neurostimulation of brain neurological movement disorders, for treating Parkinson’s disease and other involuntary movements.

He developed the first Italian project on the study of genetic disease and Parkinson’s dystonia, which led to the discovery of two new genetic loci. Also prof. Albanese is actively engaged in research in the field of semiotics detailed definition of involuntary movements, which allows tracking of related clinical pathology for accurate diagnosis of patients with movement disorders.

Prof. Albanese has published more than 200 scientific papers, most of which are published in indexed journals (with a total impact factor>500), is the author of one monograph, 3 books and co-author of numerous books and publications. He is the chief editor of “Frontiers in Movement Disorders” and assistant editor of the “European Journal of Neuroscience”.

Publications: http://www.ncbi.nlm.nih.gov/pubmed?term=albanese a

Prof. Alessandro Castagna is the Orthopedic Surgery of the Shoulder and Elbow Unit Director in Humanitas Research Hospital. He performs both traditional surgeries and arthroscopic surgeries. He developed experience in arthroscopic surgery of the shoulder in the United States where he studied at the Southern California Orthopedic Institute, under the guidance of Dr. Stephen J. Snyder (famous shoulder surgeon, inventor and co-developer of surgical tools for shoulder arthroscopy).

Prof. Castagna gained experience in open surgery of the shoulder under the guidance of Prof. Mario Randelli, founder and past-president of the Italian Society for Surgery of the Shoulder, in Milan (Italy). He has specialized almost exclusively in shoulder surgery for more than 25 years and counts over 40.000 cases in his career. He carries out about 900 surgeries per year, including total shoulder prostheses, reverse prostheses, open and arthroscopic stabilization, rotator cuff repair and proximal humerus fractures.

Research areas of interest: 

Improvement of surgical and therapeutic methods of shoulder pathology. He gives particular attention to the study of biological and functional aspects with the development of surgical techniques, materials and dedicated tools. 

Teaching experience: Adjunct Professor at the Orthopedics Course of Specialization in Diseases of the Locomotor System at the University of L'Aquila.

Scientific activity: 

Prof. Castagna was president of European Society for Surgery of the Shoulder and the Elbow (ESSSE/SECEC) (www.secec.org) from 2012 to 2014 and president of Italian Society for Surgery of the Shoulder and Elbow (SICS&G) (www.sicseg.it) from 2010 to 2012. He is also a Member of the Board di International Congress of Shoulder and Elbow Surgery (ICSES, www.icses.org) nominated for the period from 2013 to 2022.

Publications: http://www.ncbi.nlm.nih.gov/pubmed/?term=castagna+alessandro

Prof. Alessio Michele Goffredo Aghemo is the Hepatology Unit Director in Humanitas research Hospital.

Medical areas of interest: 

• liver diseases
• viral hepatitis
• metabolic hepatitis
• liver cirrhosis

Previous experience: 

From 2007 to 2017 he was the 1st level Medical Director at the U.O of Gastroenterology of the IRCCS Foundation Ca' Granda Ospedale Maggiore Policlinico, Milan.

Research areas of interest: 

Clinical and research activity focused on natural history and treatment of viral hepatitis.

He is the author of 155 peer-reviewed publications (Impact Factor total 1151.3, H-Index 25 according to Scopus, H-Index 20 last 5 years Scopus, H-Index 30 according to Google Scholar) (updated September 2017).

From 2013 to 2016 he was a scientific member of the governing board of the European Association for the Study of the Liver (EASL).

Since 2016 he is a member of the scientific committee of the European Association of Gastroenterology (UEG).

He is a member of the AISF (Italian Association for the Study of the Liver) commission for antiviral drugs directed against HCV (2012-present). Since 2016 he has been the coordinator of the same. 

He was AIFA/EMEA expert for liver disease since 2008.

Member of the Executive Committee of the HCV Regional Network, determined by the Lombardy Region on 28 September 2015.

He participated as an expert in the drafting of the European Guidelines 2013-2014-2015-2016-2017 (EASL) and Italian (AISF) on the Treatment of Chronic Hepatitis C.

Teaching experience:

He is associated professor of Gastroenterology at Humanitas University since September 2017.

Prof. Antonio Costanzo is the Dermatology Unit Director in Humanitas Research Hospital. He graduated with his MD degree in Medicine and Surgery from the University of Rome, La Sapienza in 1994. He then went on to complete post-graduate study and received a speciality degree in Internal Medicine in 1999 and a Dermatology speciality degree in 2006.

Medical areas of interest:

• Inflammatory and autoimmune skin diseases (Psoriasis, Atopic Dermatitis, Alopecia Areata, Chronic Urticaria, Suppurative Hydroadenitis, Scleroderma, Lupus)
• Personalized Medicine, Biological Psoriasis Therapy
• Dermatological Oncology (Melanoma, Actinic Keratosis, Basocellular and Spinocellular Epitheliomas).
• Prevention of skin neoplasms (dermatoscopy, computer mapping of moles).
• Dermatological surgery

Previous experience:

• Director of Dermatology Unit at Sant’Andrea Hospital in Vercelli
• University Researcher/Hospital Assistant at Tor Vergata Hospital 

Research areas of interest: 

• Psoriasis pathogenesis of other inflammatory and autoimmune skin diseases
• Pathogenesis of skin neoplasms
• Genetic disorders of the skin

His clinical research is focused on the characterization of the activity of biologics in psoriasis and psoriatic arthritis. This research is strictly linked to basic research activity on the pathogenesis of psoriasis and on the use of pharmacogenetic approach to predict the efficacy and safety of biologics in psoriasis.

In the past, Professor Costanzo has collaborated to the characterization of basic mechanisms of TNF inflammatory signalling in epithelial cells and NFkappaB regulation by different stimuli. More recently his research group has collaborated to the discovery of IL-21 as critical mediator of keratinocyte proliferation in psoriasis. Professor Costanzo has authored or co-authored more than 120 publications in internationally peer-reviewed journals.

Teaching experience: Full Professor of Dermatology at Humanitas University

Publications: https://www.ncbi.nlm.nih.gov/pubmed/?term=Costanzo+A