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Bone Marrow Transpartation Clinics in Turkey

We`ve found 8 specialized hospitals for bone marrow transplantation

Bone marrow transplant in Turkey: centers and costs. Bookimed video

  • What is autologous stem cell transplantation?
  • What is allogeneic stem cell transplant?
  • What is bone marrow transplant success rate?
  • What Turkish clinics are specialized in BMT procedure?
  • How to choose a doctor for BMT in Turkey?
Bookimed Senior Doctor-Coordinator Zeeshan Zaman answers on these and other questions.
With the Bookimed support, 274 patients received individual program for bone marrow transplantation
How much bone marrow transplant costs
Timing of response 9
Doctor's qualification 10
Medical equipment 10
Service and comfort 10
Popularity of the clinic 9
After treatment, Bookimed will return 3% of the cost of treatment
BMT in children is carried out here
446 patients received a treatment program
With the Bookimed support, 446 patients received individual treatment program in Medical Park Hospitals Group
31 requests this month

Medical Park gives a special price for Bookimed patients

Cost of a bone marrow transplant at Medical Park

Prices for bone marrow transplantation in Medical Park Clinic for Bookimed patients are lower than in other Turkish clinics:

  • autologous transplant - $ 50,000
  • allogeneic transplantation (from a related donor) - $ 86,000
  • allogeneic transplant (from an unrelated donor) - $ 120,000.

Why do patients choose Medical Park?

Medical Park Hospitals Group is the largest in Turkey. More than 600 bone marrow surgeries are conducted here annualy. The Clinic collaborates with international Bone Marrow Donor Banks. Medical Park is accredited by the European Committee on Organ Transplantation.

Doctors in the Clinic provide treatment for adults and children with blood cancers or disorders: leukemia, lymphoma, various types of anemia (aplastic anemia, Fanconi anaemia, thalassemias) and other.

Who performs the treatment?

Pediatric bone marrow transplant procedure is provided by the best Medical Park onco-hematologists - Prof. Akif Yeşilipek (30 years of experience) and Prof. Tunç Fişgin (21 years of experience).

Timing of response 9
Doctor's qualification 10
Medical equipment 10
Service and comfort 10
Popularity of the clinic 10
1398 patients received a treatment program
With the Bookimed support, 1398 patients received individual treatment program in Anadolu Medical Center
3 requests for 24 hours

No. 1 onco-hematologist in Turkey works in Anadolu Clinic

What is specialty in Anadolu Hospital?

The Center of Stem Cell Transplantation at the Anadolu Medical Center belongs to TOP 5 medical institutions in Europe. The Center receives only patients older than 18 years for autologous (own cells) transplant and allogeneic (donor cells) BMT, as a stem cell transplant in children is not conducted in Anadolu Hospital. During the last 5 years Anadolu doctors have carried more than 1,000 surgeries (200 - to foreign patients).

The Transplant Department is based on two floors and equipped with 22 single wards and 16 wards of the Hematology Department. The risk of infection is brought to nought due to the high-efficiency particulate (HEPA) air-filters established in the patients wards, nursing rooms and corridors.

Who provides a bone marrow transplant?

A bone marrow transplant at the Anadolu Medical Center is provided by the Head of the Department, an international expert Prof. Zafer Gülbaş. Professor studied and worked in Turkey, Israel, the USA and Canada. Prof. Gülbaş has more than 30 years of experience in hematology practice, making him the most authoritative hematology specialist in the country.

What is the bone marrow transplant cost at Anadolu?

The cost of autologous (own bone marrow) transplant - $ 55,000.

The cost of allogeneic bone marrow transplant:

  • from a related donor - $ 95,000;
  • from an unrelated donor - $ 170,000.
All reviews (17) More

Bone marrow transplant in Turkey

Bone marrow transplantation is a medical procedure to treat a number of diseases. It is aimed at restoring the patient's normal blood formation. The first operation of this kind was performed in 1968 and since that time the need for it has been constantly increasing. Every year more than a million transplants are carried out in the world.

Which diseases do require transplantation?

Indications and contraindications for BMT

Types of bone marrow transplant in Turkey

Diagnostics before the bone marrow transplant

Bone marrow transplantation procedure in Turkey

Rehabilitation after bone marrow transplant in Turkey

Survivability prognoses after transplantation

Cost of a bone marrow transplant in Turkey

Only in Turkey

The efficiency of bone marrow transplantation is more than 95%.

The cost of the transplant is 50% less than in Europe.

Diseases treatable with BM transplant

Bone marrow transplantation is prescribed for the following diseases:

  • Cancer:
  • Leukemia;
  • Lymphoma;
  • Melanoma;
  • Myelodysplasia;
  • Myelofibrosis;
  • Plasma cell myeloma;
  • Breast cancer;
  • Ovarian сancer.
  • Immune system disorders:
  • Beta-thalassemia;
  • Immunodeficiencies;
  • Multiple sclerosis;
  • Lupus erythematosus;
  • Blood disorders:
  • Aplastic anemia;
  • Sickle cell anemia.
  • Metabolic diseases.

Indications and contraindications for bone marrow transplant

Indication for transplantation of bone marrow is achieving a condition in which own blood-forming tissue can not cope with its function. In non-cancer diseases it is the lack of production of stem cells, in leukosis it is their production in “immature” state.

Contraindications to the procedure are:

  • Acute infectious diseases (hepatitis B and the C, syphilis, HIV).
  • Diseases of the immune system.
  • Severe diseases of internal organs.
  • Pregnancy.
  • Elderly age.
  • Long-term taking of hormonal drugs or antibiotics.

Types of bone marrow transplantation in Turkey

Transplant surgeries are divided according to the source of producing hematopoietic material for transplantation into:

- Autologous (transplantation of own hematopoietic cells, taken earlier).

- Homogeneous (material is transplanted from another person):

  • related – of a close relative. A particular case of this type of transplant is syngenesiotransplantation, where the material of the twin is transplanted.
  • unrelated –of an unrelated donor.

Autologous transplant is conducted to the patients with malignant tumors if the cancer has not affected bone marrow tissue or disease went into remission. It is important to conduct the transplantation before the tumor becomes resistant to treatment. This type of transplant does not create compatibility problems, which becomes the main when it is allogeneic.

Transplanted bone marrow must genetically match the tissues of the recipient. Otherwise there is a risk of complications of two types:

  • Graft-versus-host when the transplanted cells perceive the recipient’s cells as “alien” and begin to attack them. The occurrence of such complication is extremely dangerous for the patient. In order to suppress the reaction, the drugs that suppress the immune system,immunosuppressants are assigned.
  • Rejection reaction when the patient's immune system destroys the transplanted stem cells.

To prevent these reactions, the doctors of Turkish hospitals carefully select donor for allogeneic transplantation. The opportunity to use the close relatives - the patient’s brothers and sisters - as the donors are carefully checked. Pediatric patients have even higher chances as one of the parents can be a donor. If to pick up a related donor is not possible, specialists in Turkish hospitals choose unrelated donors in the Bone Marrow Donors Worldwide. In this case the genetic compatibility is more than 35%.

Diagnostics before transplant

In the clinics of Turkey, a patient and a donor have to undergo diagnostic procedures prior to the appointment of the procedure and the prevention of complications. They include:

  • Biochemical analysis of blood (including tests for glucose, creatinine, total protein and others);
  • Bone marrow aspiration;
  • Pneumonography;
  • Testing of lung function;
  • Electrocardiogram.

To identify the compatibility, the additional examinations are conducted:

  • histocompatibility (HLA) and blood type;
  • mixed leukocyte reaction;
  • test for chimeric genes;
  • pregnancy test (for female donors).

Bone marrow transplant procedure in Turkey

The Turkish clinics conduct the transplantation at six phases:

  1. Preparation. A preliminary course of chemotherapy and radiation therapy for cancer patients to kill cancer cells of hematopoietic tissue. The course lasts for 7-10 days.
  2. Collection. The needle is placed under the ilium or femoral bones, collecting the bone marrow. The amount of seized material is 2,000 ml. Collection is conducted under anaesthesia
  3. Processing. From the obtained composition specialists delaminate healthy stem cells, which are frozen at -80°C. To reduce the risk of rejection, T-lymphocytes are extracted from it. Processing lasts for 1-2 days.
  4. Transplantation. The obtained composition is inserted to the recipient by intravenous injection. The procedure is similar to a blood transfusion and lasts for two hours.
  5. Neutropenia. This means the phase of adaptation of the stem cells in the body. In the period of neutropenia leukocytes in blood are practically absent, so the immunity is significantly impaired. To prevent infection, the patient is placed in a special sterile box and prescribed to take antibacterial and antifungal drugs. The duration of neutropenia lasts for 2-4 weeks.
  6. Engraftment. If the procedure is successful, the patient's immune system is gradually recovering. To monitor the recovery process at this phase, the Turkish doctors carry out daily tests of the blood, gradually stopping the antibiotic treatment.

Rehabilitation after transplant

The rehabilitation process is associated primarily with the restoration of the patient's immune system. During this period it is necessary for the patient to limit communication and appearance in public places. (S)he should also carefully maintain good personal hygiene. Including the recommended usage of the protective bandage when leaving the house, ш recommend using a protective bandage. All the requirements are met in order to reduce the risk of infection. A year later, the patient takes vaccination against certain diseases.

During the period of rehabilitation attending doctors prescribe periodic examinations and analyzes to monitor the recovery of the body.

Recovery prognosis after bone marrow transplantation in Turkey

The survivability prognosis depends on the disease, the type of procedure, compatibility of the recipient and donor, and other factors. In Turkish hospitals it is on average 95% for adults and almost 100% for children.

Cost of the bone marrow transplant in Turkey

The cost for the bone marrow transplant in Turkey is almost 50% lower than in the similar clinics in Europe and the USA. In addition, accommodation in the country at the time of treatment and the price of basic necessities are significantly lower than in European countries. It should also be noted that Turkey has a lot of affordable resorts recommended for rehabilitation.

Review of the patient after the bone marrow transplant in Turkey

My child was hospitalized in the Turkish clinic with chronic leukemia. Unfortunately, the chemotherapy had not given the positive results, we needed a bone marrow transplant arose. Doctors recommended us to search for a donor among family members. We passed the tests and, fortunately, the sister appeared as an appropriate donor. Many thanks to the Turkish doctors, they literally were near my son all the time until he began to get better. It's been two years, and we still remember them fondly.

Natali, Tbilisi

Timing of response 9
Doctor's qualification 10
Medical equipment 10
Service and comfort 9
Popularity of the clinic 9
BMT in children is carried out here
771 patients received a treatment program
With the Bookimed support, 771 patients received individual treatment program in Medipol Mega Hastaneler Kompleksi

Why do patients choose Medipol Mega University Hospital?

The Medipol Mega University Hospital is among top Turkish hospitals with international accreditation of JCI. Bone marrow transplant procedure for adults and children are provided at the Center for Bone Marrow Transplant at Medipol. The bone marrow transplant success rate in Medipol Hospital is 92.5%. The amount of pediatric BM transplant in 2016 is about 100.

Bone marrow specialists in the Clinic

Stem cell transplant is performed by Assistant Prof. Sema Aktaş and Assistant Prof. Ebru Erbayat Altay - the most authoritative pediatric hematologists in Turkey. BMT for adults is carried out by Professor with 35 years of experience MD Deniz Sargin. She has performed hundreds of successful transplants of stem cells and bone marrow.

How much does a bone marrow transplant procedure cost?

  • Autologous bone marrow transplant - $ 50,000.
  • Allogeneic bone marrow transplant from a related donor - $ 75,000.
  • Allogeneic bone marrow transplantation from an unrelated donor - $ 135,000.
All reviews (4) More
Timing of response 8
Doctor's qualification 9
Medical equipment 9
Service and comfort 10
Popularity of the clinic 8
After treatment, Bookimed will return 3% of the cost of treatment
1727 patients received a treatment program
With the Bookimed support, 1727 patients received individual treatment program in LIV Hospital
17 requests for week
LIV Hospital Group consists of multi-specialized Turkish hospital with two divisions of LIV Hospital Ankara, and LIV Hospital Istanbul (Ulus). Both of them are smart hospitals of new generation with all the medical technologies available in the world: da Vinci robot-assisted system for the surgeries, MAKOplasty for knee replacement, YAG Laser for vascular surgery, virtual angiography for cardiac diagnostics, etc. In 2016, LIV hospital had the best success rate among all Turkish hospitals. Three LIV centers are entitled as the Centers of Excellence.
All reviews (14) More
Yeditepe University Hospital is a multidisciplinary medical center created on the basis of Turkish medical university in Istanbul. The clinic includes 15 highly-specialized centers and is one of the largest in the country. It performs different types of organ transplantations for both children and adults. Yeditepe is known for its rigorous attitude towards cleanliness and is going to open the first in the world completely antibacterial hospital this year.
146 patients received a treatment program
With the Bookimed support, 146 patients received individual treatment program in Florence Nightingale Hospital
Florence Nightingale Hospitals was accredited by the Joint Commission International (JCI) and ISO, guarantees a high level of medical services.
Timing of response 4
Doctor's qualification 9
Medical equipment 9
Service and comfort 7
Popularity of the clinic 9
1124 patients received a treatment program
With the Bookimed support, 1124 patients received individual treatment program in Acibadem Health Group
Acibadem Healthcare Group is a leading network of hospitals in Turkey for providing health services, which includes 14 multispecialty hospitals of the country.
73 patients received a treatment program
With the Bookimed support, 73 patients received individual treatment program in American Hospital Istanbul (Koc Healthcare)
American Hospital in Istanbul was founded in 1920. In 2002, the Hospital was accredited by JCI (USA). The clinic serves about 140 thousand patients annually. American hospital is a diversified institution that operates in 38 medical branches.
All reviews (1)
It was very expensive visit and cost me almost 300$ for a wile , beside that I think they should put an English speaking employees in the american hospital
748 patients received a treatment program
With the Bookimed support, 748 patients received individual treatment program in Memorial Healthcare Group
Hospital Network Memorial is a complex of 8 specialized clinics which conduct organ transplantation, artificial insemination, genetic researches, treatment of oncological and heart diseases and a lot of other procedures. Clinic is experienced in working with international patients and serious illnesses. It shows good indicators in cancer treatment. Among other services offered by Memorial are plastic surgery, sanatorium and rehabilitation programs. The price policy is acceptable in all directions.
All reviews (5) More
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